EnnHealth · Alcohol Use Care
Your options

Medication to stop drinking

Three medications are FDA-approved for alcohol use disorder. They work differently, and the right one depends on your goal, your health history, and what you are willing to take daily.

The three FDA-approved options

Naltrexone

Reduces reward and craving

Blocks the opioid receptors alcohol acts on, so drinking becomes less rewarding. Works whether your goal is drinking less or stopping. Non-addictive, not a controlled substance. Taken as a daily pill. This is what we most commonly prescribe.

Acamprosate

Supports maintained abstinence

Thought to help stabilise brain chemistry after drinking stops. Generally used once someone has already stopped, rather than to reduce ongoing drinking. Taken three times daily, which some people find harder to sustain.

Disulfiram (Antabuse)

Deterrent

Causes an unpleasant physical reaction if you drink — flushing, nausea, a racing heart. It works by deterrence rather than by reducing craving, and it requires complete abstinence. Suited to a narrower group of people.

How the choice is actually made

The honest answer is that it depends less on which medication is "best" and more on what you want. If your goal is to cut down rather than quit entirely, disulfiram is a poor fit by design. If you have already stopped and want to stay stopped, acamprosate may make sense. If you are still drinking and want the pull to weaken, naltrexone is the most studied option for exactly that.

Your health history matters too — kidney function, liver function, and especially any opioid use, including prescription pain medication.

One important safety check Naltrexone is not safe to combine with opioids, including prescription pain medication. Your provider screens for this and other contraindications during your evaluation. Individual results vary, and naltrexone is not a substitute for emergency or detox care.
If you drink daily or heavily, read this first Stopping suddenly after sustained heavy drinking can cause withdrawal that is medically serious — shaking, sweating, a racing heart, confusion, or seizures. Do not stop on your own to "get ready" for treatment. Tell your provider how much and how often you drink; that information shapes how treatment is started safely. If you are in medical distress, call 911.

What it costs

Cash-pay — $149/month

  • Initial 45–60 minute evaluation
  • Naltrexone prescription, if appropriate for you
  • Monthly follow-up visits
  • Direct messaging with your provider

Medication is billed separately — generic naltrexone runs roughly $15–60/month at most pharmacies.

Insurance

  • Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Oscar, Ambetter, Medicare, Tricare, VA CCN, Carelon
  • Typical copay $0–$40 per visit

Benefit verification is required before your first visit — we confirm your coverage at no charge.

Ready when you are.

A 45–60 minute video evaluation with a board-certified psychiatric provider. Same-week appointments are typical.

Common questions

There is no single answer that applies to everyone. Naltrexone has the strongest evidence for reducing heavy drinking and is the most widely used for people who are still drinking. Acamprosate is aimed at maintaining abstinence after stopping. Effectiveness depends heavily on matching the medication to your goal.

Naltrexone and acamprosate are not controlled substances and can be prescribed via telehealth by a licensed provider. We prescribe naltrexone most commonly; your provider will discuss alternatives if it is not the right fit.

Not for naltrexone — it is routinely started while someone is still drinking. Acamprosate is generally begun after stopping. Either way, tell your provider your actual drinking pattern, because it affects how treatment starts safely.

No. None of the three are controlled substances, and none produce a high or cause withdrawal when discontinued.

This page is general health information, not medical advice, and does not create a provider–patient relationship. Only a licensed provider can diagnose alcohol use disorder or determine whether a particular medication is appropriate for you, after a full evaluation. Individual results vary. EnnHealth provides outpatient telehealth care and is not a detox or emergency service.