What naltrexone actually does
Alcohol triggers a release of endorphins that bind to opioid receptors in the brain. That binding is a large part of what makes drinking feel rewarding, and what makes the next drink feel compelling. Naltrexone is an opioid antagonist — it occupies those receptors without activating them, so alcohol produces less of the reward it otherwise would.
The practical effect most people describe is not dramatic. It is that the pull weakens: the second drink is less automatic, and stopping is less of a fight. It has been FDA-approved for alcohol use disorder since 1994 and is supported by more than thirty years of research.
What naltrexone is not
- Not a controlled substance. No high, no withdrawal when you stop, no diversion risk.
- Not a sedative. It does not affect energy, mood, or your ability to work and drive.
- Not disulfiram (Antabuse). It will not make you violently ill if you drink.
- Not a lifelong commitment. Many people take it for six to twelve months and stop.
Side effects, honestly
Most people tolerate naltrexone well. The common side effects — mild nausea, headache, sometimes trouble sleeping in the first week — usually fade within one to two weeks. They are most noticeable early and often improve by taking the dose with food. Your provider will talk through what to expect and what would warrant a change.
How you get it
- Book an evaluation. 45–60 minutes by secure video. You will discuss your drinking, health history, and what you actually want to change.
- Get your prescription. If naltrexone is appropriate for you, it goes to the pharmacy you choose. Most people start within a week.
- Monthly check-ins. Short follow-ups to adjust the dose and talk through how it is going.
What it costs
Cash-pay — $149/month
- Initial 45–60 minute evaluation
- Naltrexone prescription, if appropriate for you
- Monthly follow-up visits
- Direct messaging with your provider
Medication is billed separately — generic naltrexone runs roughly $15–60/month at most pharmacies.
Insurance
- Aetna, BCBS, Cigna, UnitedHealthcare, Humana, Oscar, Ambetter, Medicare, Tricare, VA CCN, Carelon
- Typical copay $0–$40 per visit
Benefit verification is required before your first visit — we confirm your coverage at no charge.
Ready when you are.
A 45–60 minute video evaluation with a board-certified psychiatric provider. Same-week appointments are typical.